PANDAS

Pediatric Autoimmune Disorders Associated with Streptococcal Infections is a hypothesis that there exists a subset of children with rapid onset of obsessive-compulsive disorders or tic disorders, and these symptoms are caused by group A beta-hemolytic streptococcal infections. The long-term outcome of PANDAS is hopeful. It is currently believed through follow up conversations with parents that only 2-3% of all pediatric cases have recurring issues into young adulthood, giving PANDAS a high recovery rate over time. Some young adults still had some type of symptoms present, but they were able to be managed through medications or they were so minute, they did not impede the person’s life, and no medication was even needed. Treatment of PANDAS usually lies in treating the Strep infection which triggered the OCD behaviors and seems to depend on: severity of initial episode, number of recurrences, family history, and many other factors.

PANS

This is a newer term used to describe the larger class of acute-onset Neuropsychiatric Syndrome and includes all cases of acute onset OCD, not just those associated with streptococcal infections. Like PANDAS, treatment of the underlying infection generally leads to very positive outcomes. Since PANS is a disease which is still undergoing much study, treatment is found in first diagnosing the condition. Though different from PANDAS, those with PANS often receive the same treatment as PANDAS, such as antibiotic and homeopathic medicines. Stanford has a comprehensive website devoted to both PANDAS and PANS.

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